Ultrastructure expansion microscopy of murine male germ cells reveals the fine molecular structures of centrioles (shown in the enlarged image). DNA is stained in blue, and the chromosome axis in red.

Researchers have found that germ cells, which develop into eggs and sperm, drive sex-dependent differences in lifespan in vertebrates. Female and male germ cells increase and reduce lifespan, ...

Seminoma, a type of testicular cancer that predominantly affects young men, is the most common testicular germ cell tumor and is characterized by its similarity to primordial germ cells (PGCs), the ...

The median age at diagnosis was 26 years, with a male predominance (96.3%). Common histological subtypes included seminoma (34.3%) and yolk sac tumor (31.3%). First-line chemotherapy comprised ...

In the absence of TLE6, the structural integrity of SCMC is compromised, and consequently cell division in the embryo fails after the two-cell stage, resulting in embryo fragmentation and death. There ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...