Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.
Mammalian oocytes utilize a conserved combination of cell cycle control, cytoskeletal organization, and polarity pathways that are fundamentally shared with other vertebrates and invertebrates.
Parasites lacking ARK1 failed to complete their development in vertebrate host cells or mosquitoes, preventing them from spreading disease. Given the importance of ARK1 for malaria parasites, this ...
The Editorial Board of the Proceedings of the National Academy of Sciences (PNAS) has selected six papers published by PNAS in 2025 to receive the Cozzarelli Prize, an award that recognizes ...
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Newly found giant DNA Ushikuvirus may offer clues to cell evolution
A giant DNA virus pulled from a Japanese freshwater pond is forcing scientists to rethink how complex cells first acquired their defining feature: the nucleus. Named ushikuvirus, the newly ...
Every second, hundreds to thousands of molecules move through thousands of nuclear pores in each of your cells. A new high-definition view reveals the machine in action.
The story of life’s beginnings gets stranger when you look closely at viruses. These tiny entities seem to sit at the edge of ...
When Associate Professor Eliezer Calo PhD '11 was applying for faculty positions, he was drawn to MIT not only because it's ...
6d
Microbial ancestor of complex life was more sophisticated than previously thought, studies suggest
Our single-celled ancestor lived in a world without plants, animals or oxygen-rich oceans. Yet, this seemingly simple microorganism took the first steps toward complex life. From this ancestor emerged ...
The origin of the nucleus remains hotly debated among scientists, but new imaging and genomic data are shedding light on this billion-year-old mystery.
Scientists are trying to understand how complex life emerged on Earth about 2 billion years ago. Our microbial ancestors could be the key.
Scientists are trying to understand how complex life emerged on Earth about 2 billion years ago. Our microbial ancestors could be the key.
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