A mathematical model could help reduce the experimental effort needed to develop production processes for gene therapies. The digital twin, developed by a team at University College London (UCL) in ...

PHILADELPHIA--(BUSINESS WIRE)--VintaBio, a biotech manufacturer specializing in high-yield, high-purity viral vectors for gene therapy, today presented data further demonstrating the advantages and ...

Viral vectors dominate gene therapy, with lentivirus, adenovirus, and AAV being key players, each with unique advantages and limitations. Non-viral vectors, such as lipid nanoparticles and GalNAc, ...

Vaccines are arguably one of the most important medical innovations in human history. When it comes to which diseases have successfully been targeted with vaccines, however, the playing field is far ...

Efficient viral vector production is essential for the cost-effective manufacture of cell and gene therapies. Many of the current production workflows are reliant on basal media in batch-mode, which ...

Transfection techniques are pivotal advances in molecular biology that allow scientists to reliably introduce DNA, RNA, ribonucleoproteins (RNPs), and other molecules into cells. Several delivery ...

This research investigates how to optimize mRNA transfection in human T-cells utilizing the jetMESSENGER ® transfection reagent. By using advanced bioanalytical instruments like the Incucyte ® ...