This newly published review article offers a comprehensive examination of the complexities of tumor angiogenesis and the origins of endothelial cells (ECs) within tumors. Tumor angiogenesis, a ...

Image Caption: Sources of vascular endothelium in hypoxic angiogenesis. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on ...

Breast cancer, the most common cancer among women, is notorious for its ability to develop resistance to a wide range of treatments, including surgery, chemotherapy, targeted therapies, and ...

Phase 2 study of atezolizumab with carboplatin plus pemetrexed followed by maintenance atezolizumab with pemetrexed for elderly patients with advanced non-squamous non-small cell lung cancer: ...

Innovative diagnostic approaches: Serum protein markers in renal cell carcinoma. Comprehensive proteomic profiling of plasma samples associated with response or resistance to immune checkpoint ...

Douglas Hanahan (left), the former Director of the Swiss Institute for Experimental Cancer Research (ISREC) at EPFL, works in the Agora Translational Cancer Research Center as a member of the Ludwig ...

Researchers from Washington University School of Medicine performed studies to assess the role of ZBTB46, a repressive transcription factor and a marker for classical dendritic cells (DCs), in tumor ...

Although the primary endpoint was not met, axitinib was associated with significantly increased PFS and ORR for patients with previously-treated, advanced extrapancreatic neuroendocrine tumors.

Although physiological immune responses require increased tissue vasculature, many solid tumors simultaneously activate angiogenesis to meet the increasing demand for oxygen and nutrients while ...