Establishment of the Immunotoxicity AOP Framework: The binding of PCP to TLR5 was identified as the molecular initiating event. This event triggers a series of key events, activation of the TLR ...
On immune cells, Toll-like receptors are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, ...
Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...
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