Sermorelin, a synthetic peptide composed of the first 29 amino acids of the endogenous growth-hormone–releasing hormone (GHRH), has long captured scientific curiosity for its structural precision and ...
BUFFALO, N.Y. — When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and ...
A GPS-like technique has been used to track G protein-coupled receptor movement, revealing how these essential receptors function. Although G protein-coupled receptors (GPCRs) are crucial to the ...
Adhesion G protein-coupled receptors have a large extracellular region (shown in green and orange) that extends into space outside the cell. Almost 35% of drugs approved by the Food and Drug ...
A preclinical study by Weill Cornell Medicine investigators shows that a specific human genetic variant of a receptor that stimulates insulin release may help individuals resist obesity. The ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 31 (August 2, 2022), pp. 1-8 (8 pages) The bacteria-derived formyl peptide fMet-Leu-Phe (fMLF) is a ...
Researchers have uncovered the structure of a known, widespread human taste receptor, which may help scientists understand the role it plays outside the tongue. “What we found was totally unexpected,” ...
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Thermodynamic insights into histamine H1 receptor ligand binding
G-protein-coupled receptors (GPCRs) are one of the largest families of cell surface proteins in the human body that recognize hormones, neurotransmitters, and drugs. These receptors regulate a wide ...
When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...
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